Methyl 2,4-dihydroxypyriMidine-5-carboxylate - Names and Identifiers
Name | 5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-2,4-dioxo-, methyl ester
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Synonyms | 158609 RARECHEM AL BF 0788 dihydroxypyriMidine-5-carboxylate Methyl 2,4-dihydroxypyriMidine-5-carboxylate Methyl 2,4-dioxo-1,2,3,4-tetrahydropyriMidine-5-carboxylate 2,4-DIOXO-1,2,3,4-TETRAHYDRO-PYRIMIDINE-5-CARBOXYLIC ACID M 1,2,3,4-Tetrahydro-2,4-dioxo-5-pyrimidinecarboxylic acid methyl ester 2,4-DIOXO-1,2,3,4-TETRAHYDRO-PYRIMIDINE-5-CARBOXYLIC ACID METHYL ESTER 5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-2,4-dioxo-, methyl ester
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CAS | 42821-92-1
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Methyl 2,4-dihydroxypyriMidine-5-carboxylate - Physico-chemical Properties
Molecular Formula | C6H6N2O4
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Molar Mass | 170.12 |
Density | 1.412 |
Melting Point | 282℃ |
pKa | 7.06±0.10(Predicted) |
Storage Condition | 2-8°C |
Methyl 2,4-dihydroxypyriMidine-5-carboxylate - Introduction
5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-2,4-dioxo-, methyl ester is an organic compound with the chemical formula C7H7N3O4. The following describes its nature, use, formulation and safety information:
Nature:
5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-2,4-dioxo-, methyl ester is a solid powder with a white or light yellow appearance. It is soluble in organic solvents such as ethanol, acetone and dimethylformamide, and slightly soluble in water. Its melting point is 140-144 degrees Celsius.
Use:
5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-2,4-dioxo-, methyl ester has anti-inflammatory and antibacterial activity in the field of medicine, and can be used to manufacture antibiotics and drug intermediates. In addition, it can also be used as an important raw material and catalyst in organic synthesis.
Preparation Method:
The preparation of 5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-2,4-dioxo-, methyl ester can be obtained by reacting pyrimidine with dimethyl methyl carbonate. The specific method is as follows: pyrimidine and dimethyl methyl carbonate are heated and reacted in the presence of alkali to form 5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-2,4-dioxo-, methyl ester, and then the product is obtained through crystallization, filtration and drying steps.
Safety Information:
5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-2,4-dioxo-, methyl ester should avoid contact with strong oxidants and strong acids to avoid dangerous reactions. Wear appropriate personal protective equipment such as chemical goggles, gloves, and protective clothing when handling. At the same time, it should be used in a well-ventilated environment, away from fire and heat sources. If skin contact occurs, rinse immediately with plenty of water and seek medical help.
Last Update:2024-04-09 21:11:58